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If you add subfolders in your mail client, they'll become labels that look like this: Folder/Subfolder. You can avoid duplicates and avoid reading the same mail twice. IMAP synchronises the actions you take in your mail client with Gmail so if you read a message in your mail client, it'll be marked as 'read' in Gmail, and it syncs your 'Sent' messages so that they will be available from any computer. IMAP (Internet message access protocol) is a protocol similar to POP that lets you download messages from a mail provider like Gmail so you can access your mail with a program like Outlook, Thunderbird or Apple Mail.
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